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LAT Polyclonal Antibody, 20ul[BT-AP04958] Lentiviral Packaging identified in the human major

SKU: 87995777840

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LAT Polyclonal Antibody, 20ul[BT-AP04958] Lentiviral Packaging identified in the human majorThe protein encoded by LAT (linker for activation of T cells) is phosphorylated by ZAP 70 Syk protein tyrosine kinases following activation of the T cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling

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Description

identified in the human major histocompatibility complex class I region

The protein encoded by this gene and three other members of the APC complex contain tetratricopeptide (TPR) repeats

298 amino acid protein that contains three WD repeats

Increased expression of CCDC88A and phosphorylation of the encoded protein may play a role in cancer metastasis

which participate in the beta-oxidation of fatty acids in mitochondria

LAT Polyclonal Antibody, 20ul[BT-AP04958] Lentiviral Packaging identified in the human majorThe protein encoded by LAT (linker for activation of T cells) is phosphorylated by ZAP 70 Syk protein tyrosine kinases following activation of the T cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling

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