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KDEL Receptor 2 Polyclonal Antibody, 50ul Mammalian Expression PTM:May be sumoylated

SKU: 90154406915

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KDEL Receptor 2 Polyclonal Antibody, 50ul Mammalian Expression PTM:May be sumoylatedRetention of resident soluble proteins in the lumen of the endoplasmic reticulum (ER) is achieved in both yeast and animal cells by their continual retrieval from the cis Golgi, or a pre Golgi compartment. Sorting of these proteins is dependent on a C terminal tetrapeptide signal, usually lys asp glu leu (KDEL) in animal cells, and his asp glu leu (HDEL) in S. cerevisiae. This process is mediated by a receptor that recognizes, and binds the

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Description

PTM:May be sumoylated

facilitating their recognition and removal

They serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities

A2M is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta

It contains N-terminal sites for myristylation and palmitylation

KDEL Receptor 2 Polyclonal Antibody, 50ul Mammalian Expression PTM:May be sumoylatedRetention of resident soluble proteins in the lumen of the endoplasmic reticulum (ER) is achieved in both yeast and animal cells by their continual retrieval from the cis Golgi, or a pre Golgi compartment. Sorting of these proteins is dependent on a C terminal tetrapeptide signal, usually lys asp glu leu (KDEL) in animal cells, and his asp glu leu (HDEL) in S. cerevisiae. This process is mediated by a receptor that recognizes, and binds the

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