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SHP-2(Phospho-Tyr542) Rabbit Polyclonal Antibody, 50ul Peptide Modification Mutations in this gene are

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SHP-2(Phospho-Tyr542) Rabbit Polyclonal Antibody, 50ul Peptide Modification Mutations in this gene areThe protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth differentiation mitotic cycle and oncogenic transformation. This PTP contains two tandem Src homology 2 domains which function as phospho tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely

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Description

Mutations in this gene are associated with type II autosomal recessive Alport syndrome (hereditary glomerulonephropathy) and with familial benign hematuria (thin basement membrane disease)

and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1

a subunit also shared by the receptor complex for interleukin 10 (IL10)

often coupled to G proteins

This gene encodes s receptor in the endoplasmic reticulum| which plays a role in the export of large pre-chylomicrons and pre-very low density lipoproteins (pre-VLDLs)

SHP-2(Phospho-Tyr542) Rabbit Polyclonal Antibody, 50ul Peptide Modification Mutations in this gene areThe protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth differentiation mitotic cycle and oncogenic transformation. This PTP contains two tandem Src homology 2 domains which function as phospho tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely

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