Rat Cop9 Signalosome Compex Subunit 1, GPS1 ELISA Kit, 96T Modification Enzymes Multiple transcript variants encoding different

Multiple transcript variants encoding different isoforms have been found for CDK10

Studies of the similar gene in Xenopus suggested that this protein play a pivotal role in the loading of DNA polymerase alpha onto chromatin

through MTOR signaling pathway activation and BCL2 up-regulation (By similarity)

this increases SRC kinase activity

PubMed: 29244122)

Rat Cop9 Signalosome Compex Subunit 1, GPS1 ELISA Kit, 96T Modification Enzymes Multiple transcript variants encoding differentEssential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53 TP53, c