MLKL mouse Monoclonal Antibody(8H7), 20ul Roller Bottles Mutations associated with this gene

Mutations associated with this gene cause autosomal recessive spastic paraplegia 13

type II) encodes a protein that belongs to the serine/threonine protein kinase family of proteins

KIF11 encodes a motor protein that belongs to the kinesin-like protein family

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the encoded protein is thought to be an important part of functional kinetochores

MLKL mouse Monoclonal Antibody(8H7), 20ul Roller Bottles Mutations associated with this geneThis gene belongs to the protein kinase superfamily. The encoded protein contains a protein kinase like domain however, is thought to be inactive because it lacks several residues required for activity. This protein plays a critical role in tumor necrosis factor (TNF) induced necroptosis, a programmed cell death process, via interaction with receptor interacting protein 3 (RIP3), which is a key signaling molecule in necroptosis pathway. Inhibitor