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KI2S2 Polyclonal Antibody, 50ul Bottle-Top Dispenser MX dynamin like GTPase 2

SKU: 91163919841

4.0
USD162.00 USD199.00

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KI2S2 Polyclonal Antibody, 50ul Bottle-Top Dispenser MX dynamin like GTPase 2Killer cell immunoglobulin like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13. 4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4,

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Description

MX dynamin like GTPase 2 encoded by MX2 has a nuclear and a cytoplasmic form and is a member of both the dynamin family and the family of large GTPases

In contrast to other members of the Ras family

Mutations in this gene have been associated with Leigh syndrome

Receptor activation by nicotinic acid results in reduced cAMP levels which may affect activity of cAMP-dependent protein kinase A and phosphorylation of target proteins

Also expressed in the synovial fluid of normal and rheumatoid patients

KI2S2 Polyclonal Antibody, 50ul Bottle-Top Dispenser MX dynamin like GTPase 2Killer cell immunoglobulin like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13. 4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4,

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