MRG15 Polyclonal Antibody, 100ul Peptide Synthesis Expression of a kinase-defective mutant

Expression of a kinase-defective mutant results in abnormal cell morphology caused by changes in microtubule dynamics and mitotic arrest followed by apoptosis

This gene is located proximal to the apolipoprotein gene cluster on chromosome 11q23

This gene encodes a member of the tumor necrosis factor receptor superfamily

The protein encoded by this gene is involved in antigen presentation

Protects cells from CD95-mediated apoptosis and is required for the increased motility and invasiveness of CD95-activated tumor cells

MRG15 Polyclonal Antibody, 100ul Peptide Synthesis Expression of a kinase-defective mutantComponent of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with