Rat Mothers Against Decapentaplegic Homolog 3, SMAD3 ELISA Kit, 96T DNA Fragments in complex with its regulatory
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Rat Mothers Against Decapentaplegic Homolog 3, SMAD3 ELISA Kit, 96T DNA Fragments in complex with its regulatoryReceptor regulated SMAD (R SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF beta and, on formation of the SMAD3 SMAD4 complex, activates transcription. Also can form a SMAD3 SMAD4 JUN FOS complex at the AP 1 SMAD site to regulate TGF beta mediated
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