CUL-1 Polyclonal Antibody, 100ul[BT-AP08191] Liquid Storage Consumables NFYC encodes one subunit of

NFYC encodes one subunit of a trimeric complex forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoters of a variety of genes

The protein is necessary for STK11-induced G1 cell cycle arrest

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PIAS2 encodes a member of the protein inhibitor of activated STAT (PIAS) family

Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway

CUL-1 Polyclonal Antibody, 100ul[BT-AP08191] Liquid Storage Consumables NFYC encodes one subunit ofCore component of multiple cullin RING based SCF (SKP1 CUL1 F box protein) E3 ubiquitin protein ligase complexes, which mediate the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as a rigid scaffold that organizes the SKP1 F box protein and RBX1 subunits. May contribute to catalysis through positioning of the substrate and the ubiquitin conjugating enzyme. The E3