LRCH2 Rabbit Polyclonal Antibody, 100ul Cell Function Analysis PPP2R1B encodes a beta isoform

PPP2R1B encodes a beta isoform of the constant regulatory subunit A

Two transcript variants encoding different isoforms have been found for NOTCH2

Rab proteins are low molecular mass GTPases that are critical regulators of vesicle trafficking

Mutation and knockout studies of the mouse gene demonstrated an essential role in adult spermatogenesis

Research also indicates a role for C5a/C5aR in the pathogenesis of rheumatoid arthritis

LRCH2 Rabbit Polyclonal Antibody, 100ul Cell Function Analysis PPP2R1B encodes a beta isoformThis gene encodes a member of the leucine rich repeat and calponin homology domain containing protein family. These family members contain multiple N terminal leucine rich repeats in addition to a C terminal calponin homology domain a type of domain that mediates interactions with actin filaments. These proteins are conserved across animal species and studies of a similar Drosophila protein indicate a function as a cytoskeletal scaffolding protein.