ErbB-3 Monoclonal Antibody, 100ul[BT-MCA0503] Insect Expression Binding of the encoded protein
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ErbB-3 Monoclonal Antibody, 100ul[BT-MCA0503] Insect Expression Binding of the encoded proteinThis gene encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the
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