SKI Polyclonal Antibody, 50ul Dry Bath DEFA4 differs from other genes

DEFA4 differs from other genes of this family by an extra 83-base segment that is apparently the result of a recent duplication within the coding region

This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions

It interacts with another ubiquitin protease and an E3 ubiquitin ligase that inhibits cytokine gene transcription in the immune system

This gene is a member of the inhibitor of apoptosis (IAP) gene family| which encode negative regulatory proteins that prevent apoptotic cell death

N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors

SKI Polyclonal Antibody, 50ul Dry Bath DEFA4 differs from other genesThis gene encodes the nuclear protooncogene protein homolog of avian sarcoma viral (v ski) oncogene. It functions as a repressor of TGF beta signaling, and may play a role in neural tube development and muscle differentiation.