PLC Gamma1 Polyclonal Antibody, 100ul[BT-AP07262] Stepper sebaceous glands

sebaceous glands

The encoded protein is associated with several phenotypes- Greig cephalopolysyndactyly syndrome

The enzyme is activated by increased intracellular Ca(2+) levels and phosphorylation

The FYVE domain mediates the recruitment of proteins involved in membrane trafficking and cell signaling to phosphatidylinositol 3-phosphate-containing membranes

IQGAP1 encodes a member of the IQGAP family

PLC Gamma1 Polyclonal Antibody, 100ul[BT-AP07262] Stepper sebaceous glandsThe protein encoded by PLCG1 (phospholipase C gamma 1) catalyzes the formation of inositol 1,4,5 trisphosphate and diacylglycerol from phosphatidylinositol 4,5 bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate