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Rb Monoclonal Antibody, 50ul Bacterial Expression while the carboxy-terminal region is

SKU: 9497583932

4.3
PLN162.00 PLN195.00

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Rb Monoclonal Antibody, 50ul Bacterial Expression while the carboxy-terminal region isThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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Description

while the carboxy-terminal region is protease sensitive

This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6

This protein contains the least conserved DNA-binding domain within the Sp subfamily of proteins

Naturally occurring read-through transcription occurs between the upstream gene NPHP3 (nephronophthisis 3 (adolescent)) and this gene

This gene is intronless and encodes a member of the histone H2B family

Rb Monoclonal Antibody, 50ul Bacterial Expression while the carboxy-terminal region isThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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