HDAC5 Polyclonal Antibody, 100ul Buffer Solutions High mobility group box 1

High mobility group box 1 plays a role in several cellular processes

It is ubiquitously expressed in normal tissues and in tumor cells

One version of pediatric acute myeloid leukemia is the result of a reciprocal translocation between chromosomes 11 and X

similar to Vps4 protein in yeast

Overexpressed in a number of carcinomas

HDAC5 Polyclonal Antibody, 100ul Buffer Solutions High mobility group box 1Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation deacetylation alters chromosome structure and affects transcription factor access to DNA. Histone deacetylase 5 encoded by HDAC5 belongs to the class II histone deacetylase acuc apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with