BCL2L12 Polyclonal Antibody, 50ul Custom DNA Oligos Several transcript variants encoding multiple

Several transcript variants encoding multiple isoforms have been described

This family member functions as a scaffold protein that tethers protein kinases to the Z-disk in striated muscles

A ZFP91-related pseudogene has also been identified on chromosome 2

This protein contains 6 WD repeats and is highly expressed in the heart

in target proteins that include histones

BCL2L12 Polyclonal Antibody, 50ul Custom DNA Oligos Several transcript variants encoding multipleBCL2L12 (BCL2 like 12) encodes a member of a family of proteins containing a Bcl 2 homology domain 2 (BH2). The encoded protein is an anti apoptotic factor that acts as an inhibitor of caspases 3 and 7 in the cytoplasm. In the nucleus, it binds to the p53 tumor suppressor protein, preventing its association with target genes. Overexpression of BCL2L12 has been detected in a number of different cancers. There is a pseudogene for BCL2L12 on chromosome