PPP1R15B Polyclonal Antibody, 50ul Insect Expression An important paralog of this

An important paralog of this gene is RNF214

This gene encodes a protein that contains multiple transmembrane regions and two pore-forming P domains and functions as a pH-dependent potassium channel

The protein encoded by IPPK (inositol-pentakisphosphate 2-kinase) is a kinase that phosphorylates position 2 of inositol-1

The encoded protein

miscellaneous:The early and prominent pathology of HD is observed in the medium spiny neurons that project into the globus

PPP1R15B Polyclonal Antibody, 50ul Insect Expression An important paralog of thisPPP1R15B encodes a protein phosphatase I interacting protein that promotes the dephosphorylation of eukaryotic translation initiation factor 2A to regulate translation under conditions of cellular stress. The transcribed messenger RNA contains two upstream open reading frames (ORFs) that repress translation of the main protein coding ORF under normal conditions, while the protein coding ORF is expressed at high levels in response to stress. Continual