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Siah-1/2 Polyclonal Antibody, 20ul Low retention tips These subunits are encoded by

SKU: 96977460292

4.1
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Siah-1/2 Polyclonal Antibody, 20ul Low retention tips These subunits are encoded bySIAH1 encodes E3 ubiquitin protein ligase SIAH1 that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease, the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing

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Description

These subunits are encoded by 6 different genes

Expressed specifically in the hippocampus and Purkinje cells of the brain

No need for high-temperature flame sterilization

The neck region is important for homo-oligomerization which allows the receptor to bind multivalent ligands with high avidity

and are involved in stem cell development

Siah-1/2 Polyclonal Antibody, 20ul Low retention tips These subunits are encoded bySIAH1 encodes E3 ubiquitin protein ligase SIAH1 that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease, the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing

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