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p27(Phospho Thr198) Polyclonal Antibody, 100ul Culture Tubes The expression of this gene

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p27(Phospho Thr198) Polyclonal Antibody, 100ul Culture Tubes The expression of this geneThis gene encodes a cyclin dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A p21. The encoded protein binds to and prevents the activation of cyclin E CDK2 or cyclin D CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from

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Description

The expression of this gene is upregulated by tazarotene as well as by retinoic acid receptors

a family of secreted chemorepellants

A similar protein in mouse is a transcription factor that binds to DNA sequences almost identical to that bound by the Notch receptor signaling pathway transcription factor recombining binding protein J

This gene is clustered with genes and pseudogenes of the cell adhesion molecules subgroup of the CEA family on chromosome 19

Mutation in this gene has been associated with Naxos disease

p27(Phospho Thr198) Polyclonal Antibody, 100ul Culture Tubes The expression of this geneThis gene encodes a cyclin dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A p21. The encoded protein binds to and prevents the activation of cyclin E CDK2 or cyclin D CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from

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