CENPU Polyclonal Antibody, 100ul Lentiviral Packaging a SAPS domain-containing subunit (PP6R)

a SAPS domain-containing subunit (PP6R) and an ankyrin repeat-domain containing regulatory subunit (ARS)

Mutations in this gene are associated with forebrain defects

By use of chaotropic agents

The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form the mature protein

Alternative splicing of this gene results in two transcript variants encoding the same protein

CENPU Polyclonal Antibody, 100ul Lentiviral Packaging a SAPS domain-containing subunit (PP6R)The centromere is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on which the transient assembly of the kinetochore occurs during mitosis. All active centromeres are characterized by the presence of long arrays of nucleosomes in which CENPA (MIM 117139) replaces histone H3 (see MIM 601128). MLF1IP, or CENPU, is an additional factor required for centromere assembly (Foltz et al., 2006