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Fibulin-3 Polyclonal Antibody, 50ul Peptide Modification The polyadenylation site of CFB

SKU: 97383522364

4.4
USD185.00 USD221.00

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Fibulin-3 Polyclonal Antibody, 50ul Peptide Modification The polyadenylation site of CFBEFEMP1 encodes a member of the fibulin family of extracellular matrix glycoproteins. Like all members of this family, the EGF containing fibulin like extracellular matrix protein 1 contains tandemly repeated epidermal growth factor like repeats followed by a C terminus fibulin type domain. This gene is upregulated in malignant gliomas and may play a role in the aggressive nature of these tumors. Mutations in this gene are associated with Doyne

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Description

The polyadenylation site of CFB is 421 bp from the 5' end of the gene for complement component 2

Four transcript variants encoding different isoforms have been described for this gene

This gene is one of the contiguous genes at 7q11

GGH (gamma-glutamyl hydrolase)catalyzes the hydrolysis of folylpoly-gamma-glutamates and antifolylpoly-gamma-glutamates by the removal of gamma-linked polyglutamates and glutamate

the intestine

Fibulin-3 Polyclonal Antibody, 50ul Peptide Modification The polyadenylation site of CFBEFEMP1 encodes a member of the fibulin family of extracellular matrix glycoproteins. Like all members of this family, the EGF containing fibulin like extracellular matrix protein 1 contains tandemly repeated epidermal growth factor like repeats followed by a C terminus fibulin type domain. This gene is upregulated in malignant gliomas and may play a role in the aggressive nature of these tumors. Mutations in this gene are associated with Doyne

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