ORC3 Polyclonal Antibody, 50ul Gene Synthesis Chromatin assembly factor I (CAF1)

Chromatin assembly factor I (CAF1) is a nuclear complex consisting of p50

Defects in SLC6A11 may result in epilepsy

the encoded protein is expressed in a restricted population of normal and malignant pre-B and pre-T lymphocytes during early differentiation

The encoded protein circulates in the plasma and is involved with metabolic and hormonal processes

Its interaction with nuclear receptors is independent of the AF2 domain on the receptors

ORC3 Polyclonal Antibody, 50ul Gene Synthesis Chromatin assembly factor I (CAF1)The origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. Studies of a similar gene in