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HER2/ErbB2(Phospho-Tyr1196) Rabbit Polyclonal Antibody, 20ul Gloves Alternativley spliced transcript variants encoding

SKU: 97634237810

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HER2/ErbB2(Phospho-Tyr1196) Rabbit Polyclonal Antibody, 20ul Gloves Alternativley spliced transcript variants encodingThis gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However it does bind tightly to other ligand bound EGF receptor family members to form a heterodimer stabilizing ligand binding and enhancing kinase mediated activation of downstream signalling pathways such as those involving mitogen activated

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Description

Alternativley spliced transcript variants encoding different isoforms have been identified in this gene

There are pseudogenes for this gene on chromosomes 22 and X

The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2)

and JAK2 pathways

This gene encodes a member of the fibrillar collagen family

HER2/ErbB2(Phospho-Tyr1196) Rabbit Polyclonal Antibody, 20ul Gloves Alternativley spliced transcript variants encodingThis gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However it does bind tightly to other ligand bound EGF receptor family members to form a heterodimer stabilizing ligand binding and enhancing kinase mediated activation of downstream signalling pathways such as those involving mitogen activated

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