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HNF1 alpha(Phospho-Ser247) Rabbit Polyclonal Antibody, 100ul Sealing Film mutations in either gene may

SKU: 97647514456

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HNF1 alpha(Phospho-Ser247) Rabbit Polyclonal Antibody, 100ul Sealing Film mutations in either gene mayThe protein encoded by this gene is a transcription factor required for the expression of several liver specific genes. The encoded protein functions as a homodimer and binds to the inverted palindrome 5' GTTAATNATTAAC 3'. Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas. Alternative splicing results in multiple transcript variants encoding different

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Description

mutations in either gene may contribute to these disorders

have fewer positive charged residues that in other sodium channels

Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes| dendritic cells| macrophages)

Gene Ontology (GO) annotations related to MZF1 include transcription factor activity

Binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP

HNF1 alpha(Phospho-Ser247) Rabbit Polyclonal Antibody, 100ul Sealing Film mutations in either gene mayThe protein encoded by this gene is a transcription factor required for the expression of several liver specific genes. The encoded protein functions as a homodimer and binds to the inverted palindrome 5' GTTAATNATTAAC 3'. Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas. Alternative splicing results in multiple transcript variants encoding different

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