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Frizzled-10 Polyclonal Antibody, 100ul[BT-AP03356] Buffers & Solutions subunit:Component of a complex

SKU: 97657616896

4.2
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Frizzled-10 Polyclonal Antibody, 100ul[BT-AP03356] Buffers & Solutions subunit:Component of a complexFZD10 is a member of the frizzled gene family. Members of this family encode 7 transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta catenin canonical signaling pathway. Using array analysis, expression of this intronless gene is significantly up regulated in two cases of primary colon cancer.

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Description

subunit:Component of a complex

Play an inhibitory role on IL13 signaling by binding to IL13RA1

while CUL-2 associates with the tumor suppressing protein VHL and elongin B to form VBC complexes

Elongation factor that can increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA

Exon 1 encodes the leader peptide| exons 2 and 3 encode the two extracellular domains| exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail

Frizzled-10 Polyclonal Antibody, 100ul[BT-AP03356] Buffers & Solutions subunit:Component of a complexFZD10 is a member of the frizzled gene family. Members of this family encode 7 transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta catenin canonical signaling pathway. Using array analysis, expression of this intronless gene is significantly up regulated in two cases of primary colon cancer.

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