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ErbB-3 Polyclonal Antibody, 20ul[BT-AP03043] Funnels It is encoded by the

SKU: 98629880303

4.4
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ErbB-3 Polyclonal Antibody, 20ul[BT-AP03043] Funnels It is encoded by theERBB3 encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation

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Description

It is encoded by the single ACHE gene

Two transcript variants

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and it apparently protects neurons against oxidative stress and cell death

a recessively inherited connective-tissue disorder

ErbB-3 Polyclonal Antibody, 20ul[BT-AP03043] Funnels It is encoded by theERBB3 encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation

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