ASK 1 Polyclonal Antibody, 50ul[BT-AP00671] NGS Oligos This domain is known to

This domain is known to be involved in protein-protein interactions

Mutations in this gene have been found in patients with velocardiofacial syndrome

May act as a tumor suppressor

PTM:Phosphorylated in vitro by CLK4

SH2 and SH3 domains

ASK 1 Polyclonal Antibody, 50ul[BT-AP00671] NGS Oligos This domain is known toMitogen activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal regulated kinase (ERK), MAPK kinase (MKK or MEK), and MAPK kinase kinase (MAPKKK or MEKK). MAPKK kinase MEKK phosphorylates and activates its downstream protein kinase, MAPK kinase MEK, which in turn activates MAPK. The kinases of these signaling cascades are highly conserved, and homologs exist in yeast, Drosophila, and mammalian cells. MAPKKK5 contains