Raf-1(Phospho Ser296) Polyclonal Antibody, 50ul Pipette Filler Induces chemoresistance

Induces chemoresistance

Contains 13 laminin EGF-like domains

Negatively regulates Golgi-to-plasma membrane trafficking by interacting with PI4KB and inhibiting its activity

PLXDC1 (TEM7) is identified through serial analysis of gene expression on endothelial cells isolated from human normal and malignant colorectal tissues

It is a component of the mitochondrial network

Raf-1(Phospho Ser296) Polyclonal Antibody, 50ul Pipette Filler Induces chemoresistanceThis gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.