Tuberin(Phospho Thr1462) Polyclonal Antibody, 50ul Plasma Mitotic and Regulation of PLK1

Mitotic and Regulation of PLK1 Activity at G2/M Transition

Gene Ontology (GO) annotations related to this gene include death receptor binding

Intermediate filamentents

An important paralog of this gene is GK

The encoded protein binds to single-stranded DNA coated with replication protein A

Tuberin(Phospho Thr1462) Polyclonal Antibody, 50ul Plasma Mitotic and Regulation of PLK1Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.