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Arg Polyclonal Antibody, 100ul Liquid Handling &Storage The directionality of nuclear import

SKU: 99659579450

4.7
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Arg Polyclonal Antibody, 100ul Liquid Handling &Storage The directionality of nuclear importABL2 encodes a member of the Abelson family of nonreceptor tyrosine protein kinases. Abelson tyrosine protein kinase 2 is highly similar to the c abl oncogene 1 protein, including the tyrosine kinase, SH2 and SH3 domains, and it plays a role in cytoskeletal rearrangements through its C terminal F actin and microtubule binding sequences. This gene is expressed in both normal and tumor cells, and is involved in translocation with the ets variant 6 gene

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Description

The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus (By similarity)

and it is structurally similar to opioid and somatostatin receptors

Two alternatively spliced transcript variants of RELT encoding the same protein have been reported

The protein encoded by this gene is an alkaline phosphatase

This heterodimer binds E-box enhancer elements upstream of Period (PER1

Arg Polyclonal Antibody, 100ul Liquid Handling &Storage The directionality of nuclear importABL2 encodes a member of the Abelson family of nonreceptor tyrosine protein kinases. Abelson tyrosine protein kinase 2 is highly similar to the c abl oncogene 1 protein, including the tyrosine kinase, SH2 and SH3 domains, and it plays a role in cytoskeletal rearrangements through its C terminal F actin and microtubule binding sequences. This gene is expressed in both normal and tumor cells, and is involved in translocation with the ets variant 6 gene

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