DOC11 Polyclonal Antibody, 100ul Cell Culture MAP4 and MAPT/TAU at KXGS

MAP4 and MAPT/TAU at KXGS motifs

This gene has been linked to non-small cell lung cancer

most notably the t(9|22) translocation that results in a fusion with the 5' end of the breakpoint cluster region gene (BCR| MIM:151410)

The protein lacks the cytoplasmic domain characteristic of other cadherins

Within the sequence used as an immunogen

DOC11 Polyclonal Antibody, 100ul Cell Culture MAP4 and MAPT/TAU at KXGSThe DHR 2 domain is necessary for the GEF activity.,Guanine nucleotide exchange factor (GEF) that activates CDC42 by exchanging bound GDP for free GTP.,miscellaneous:'Zizim' means 'spike' in Hebrew.,PTM: Phosphorylated upon DNA damage, probably by ATM or ATR.,Belongs to the DOCK family.,Contains 1 DHR 1 (CZH 1) domain.,Contains 1 DHR 2 (CZH 2) domain.,Contains 1 PH domain.,subunit: Interacts with CDC42.,