Syk Polyclonal Antibody, 50ul[BT-AP08701] Variant Libraries This gene encodes an E3

This gene encodes an E3 ubiquitin ligase of the N-end rule proteolytic pathway that targets proteins with destabilizing N-terminal residues for polyubiquitylation and proteasome-mediated degradation

Mutations in this gene are associated with X-linked Alport syndrome

GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors| which are ligand-gated chloride channels

a calmodulin-binding domain (CBD)

Genetic variation in this gene may be associated with susceptibility to hereditary essential tremor 1

Syk Polyclonal Antibody, 50ul[BT-AP08701] Variant Libraries This gene encodes an E3SYK (spleen associated tyrosine kinase) encodes a member of the family of non receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human