FoxO1 Polyclonal Antibody, 100ul[BT-AP03327] Enzyme Activity Assays ASCL2 is a member of

ASCL2 is a member of the basic helix-loop-helix (BHLH) family of transcription factors

thereby physically blocking transcription

Mutations within PAX2 have been shown to result in optic nerve colobomas and renal hypoplasia

EphA4 (Hek8)

resulting in a decrease of malignant activity in cells with ectopic expression of VWA5A

FoxO1 Polyclonal Antibody, 100ul[BT-AP03327] Enzyme Activity Assays ASCL2 is a member ofFOXO1 belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in myogenic growth and differentiation. Translocation of this gene with PAX3 has been associated with alveolar rhabdomyosarcoma.