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In 2012, Mavigner et al

Orlowski M et al

This matters most for drugs with narrow therapeutic windowsmedicines where blood levels must stay within a tight range to be safe and effective

Money is paid into these funds by the lawyers representing individual plaintiffs

For example, in a resting state, glycogen synthase kinase-3 (GSK-3) phosphorylates NRF2, creating a site recognized by the E3 ligase adapter beta-transducin repeat-containing protein (-TrCP)