Triapine - CAS# 143621-35-6 0264 it was shown and used

it was shown and used to enhance the survival and cloning efficiency of many primary cell types after single cell dissociation without affecting their self-renewal properties

01-10 µM) inhibits cell proliferation in a dose- and time-dependent manner

RIPK2 inhibitor 1

(2007) Nat Biotech 25: 681-686

ISRIB potently reverses the effects of eIF2α phosphorylation (IC50=5 nM)

Triapine - CAS# 143621-35-6 0264 it was shown and usedTriapine, also known as 3 AP and OCX 191, CAS No. 143621 35 6, is a synthetic heterocyclic carboxaldehyde thiosemicarbazone with potential antineoplastic activity. Triapine inhibits the enzyme ribonucleotide reductase, resulting in the inhibition of the conversion of ribonucleoside diphosphates to deoxyribonucleotides necessary for DNA synthesis. This agent has been shown to inhibit tumor growth in vitro. Product information CAS Number: 143621 35 6