A83-01 --- an ALK inhibibitor.. CAS# 909910-43-6 size:Contact [email protected] for quotation Rajiva De Silva N

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A83-01 --- an ALK inhibibitor.. CAS# 909910-43-6 size:Contact [email protected] for quotation Rajiva De Silva NA83 01 an ALK inhibibitor., CAS No. 909910 43 6, is an ALK inhibibitor. It was found that A 83 01 inhibited the transcriptional activity induced by TGF beta type I receptor ALK 5 and that by activin type IB receptor ALK 4 and nodal type I receptor ALK 7, the kinase domains of which are structurally highly related to those of ALK 5. A 83 01 was found to be more potent in the inhibition of ALK5 than a previously described ALK 5 inhibitor, SB 431542, and

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