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ARN-509 - CAS# 956104-40-8 Size:Solid 2 mg Ionomycin-induced calcium influx induces neurite

SKU: 14337310155

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ARN-509 - CAS# 956104-40-8 Size:Solid 2 mg Ionomycin-induced calcium influx induces neuriteApalutamide, also known as ARN 509 and JNJ 56021927 , is an androgen receptor antagonist with potential antineoplastic activity. ARN 509 binds to AR in target tissues thereby preventing androgen induced receptor activation and facilitating the formation of inactive complexes that cannot be translocated to the nucleus. This prevents binding to and transcription of AR responsive genes. This ultimately inhibits the expression of genes that regulate

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Description

Ionomycin-induced calcium influx induces neurite degeneration in mouse neuroblastoma cells: analysis of a time-lapse live cell imaging system

Molecular Weight: 260

TG100-115 was also assayed against a 133 protein kinase panel

which correlates with effects on tumor growth

Dembinski JL

ARN-509 - CAS# 956104-40-8 Size:Solid 2 mg Ionomycin-induced calcium influx induces neuriteApalutamide, also known as ARN 509 and JNJ 56021927 , is an androgen receptor antagonist with potential antineoplastic activity. ARN 509 binds to AR in target tissues thereby preventing androgen induced receptor activation and facilitating the formation of inactive complexes that cannot be translocated to the nucleus. This prevents binding to and transcription of AR responsive genes. This ultimately inhibits the expression of genes that regulate

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