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WDR5-0103 - WDR5 Inhibitor. CAS# 890190-22-4 size:10mg solid 2018 Jan 11

WDR5-0103 - WDR5 Inhibitor. CAS# 890190-22-4 size:10mg solid 2018 Jan 11

Name: WDR5-0103 - WDR5 Inhibitor. CAS# 890190-22-4 size:10mg solid 2018 Jan 11
Brand: clickpoint.com.au
SKU: 15013295001
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SKU: 15013295001

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WDR5-0103 - WDR5 Inhibitor. CAS# 890190-22-4 size:10mg solid 2018 Jan 11WDR5 0103, CAS No. 890190 22 4, is a potent and selective WD repeat containing protein 5 (WDR5) antagonist with Kd of 450 nM. It has no effect on a panel of seven other methyltransferases, including SETD7. It binds in the WDR5 peptide binding pocket and inhibits the catalytic activity of the MLL core complex in vitro. WDR5 0103 is a good chemical probe to demonstrate inhibition of an important protein protein interaction and form the basis for further

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Description

2018 Jan 11

Chemical Name: (S)-N-(bis(4-fluorophenyl)methyl)-1-(2-(2-ethyl-2-isobutyramidobutanamido)-5-guanidinopentanamido)cyclopentanecarboxamide

197:138-47

blocks LPS-induced NF-kB activation

CFTR Inhibitor II

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