(R)-MG132 176 CS-0087356

CS-0087356

27 (IC50=3

It has >100-fold selectivity over a broad panel of 230 kinases

Smiles: O[C@@H]1[C@H]([C@@H](O)[C@@H](CO)O[C@H]1S[C@@H]1O[C@H](CO)[C@H](O)[C@@H]([C@H]1O)N1C=C(N=N1)C1=CC(F)=CC=C1)N1C=C(N=N1)C1=CC(F)=CC=C1

192(7):3383-9

(R)-MG132 176 CS-0087356(R) MG132 is a potent, reversible, and cell permeable proteasome inhibitor. Product information CAS Number: 1211877 36 9 Molecular Weight: 489. 65 Formula: C27H43N3O5 Synonym: Z Leu D Leu Leu al (S, R, S) ( ) MG 132 Chemical Name: N [(phenylmethoxy)carbonyl] L leucyl N [(1R) 1 formyl 3 methylbutyl] L leucinamide Smiles: CC(C)C[C@H](NC(=O)OCC1C=CC=CC=1)C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CC=O)CC(C)C InChiKey: HWFLPOLDRUQRFC SMIHKQSGSA N InChi: InChI=1S