Olcegepant - CAS# 204697-65-4 Catalog No.:M10814-10 CAS Number: 911222-45-2

CAS Number: 911222-45-2

Epub 2008 Feb 6

Smiles: O=C(NC1C=CC(=CC=1)C1=CC=NC(NC2C=CC(=CC=2)N2CCOCC2)=N1)[C@@H]1CCCN1

which may have potential application in treating anemia of chronic disease

Smiles: CC1CC[C@@H]2[C@H](OC(=O)C2=C)[C@@H]2C=1CC[C@@]2(C)O

Olcegepant - CAS# 204697-65-4 Catalog No.:M10814-10 CAS Number: 911222-45-2Olcegepant, also known as BIBN 4096 or BIBN 4096BS is is the first potent and selective non peptide antagonist of the calcitonin gene related peptide 1 (CGRP1) receptor, a key modulator in neurogenic inflammatory pain. In preclinical studies, olcegepant attenuated arterial dilation induced by CGRP or electrical stimulation. In a phase II clinical trial, olcegepant reduced the severity of headache in 60% of migraine sufferers and met secondary