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ML792 Catalog No.:M7530-10 4 nM respectively

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ML792 Catalog No.:M7530-10 4 nM respectivelyML 792 is a potent and selective inhibitor of SUMO (small ubiquitin like modifier) activating enzyme (SAE). ML 792 inhibits SAE SUMO1 and SAE SUMO2 in ATPinorganic pyrophosphate (PPi) exchange assays with IC50 of 3 nM and 11 nM, respectively. Product information CAS Number: 1644342 14 2 Molecular Weight: 551. 41 Formula: C21H23BrN6O5S Synonym: ML 792 ML 792 Chemical Name: ((1R,2S,4R) 4 ((5 (1 (3 bromobenzyl) 1H pyrazole 3 carbonyl)pyrimidin 4

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Description

4 nM respectively

5-c]pyridin-6-yl]oxy]phenyl]-4-[2-(4-morpholinyl)ethoxy]-benzamide

ADX-47273 increased (9-fold) the response to threshold concentration of glutamate (50 nM) in fluorometric Ca(2+) assays (EC(50) = 170 nM) in human embryonic kidney 293 cells expressing rat mGlu5

ALK inhibitors and advanced non-small cell lung cancer (review)

once daily

ML792 Catalog No.:M7530-10 4 nM respectivelyML 792 is a potent and selective inhibitor of SUMO (small ubiquitin like modifier) activating enzyme (SAE). ML 792 inhibits SAE SUMO1 and SAE SUMO2 in ATPinorganic pyrophosphate (PPi) exchange assays with IC50 of 3 nM and 11 nM, respectively. Product information CAS Number: 1644342 14 2 Molecular Weight: 551. 41 Formula: C21H23BrN6O5S Synonym: ML 792 ML 792 Chemical Name: ((1R,2S,4R) 4 ((5 (1 (3 bromobenzyl) 1H pyrazole 3 carbonyl)pyrimidin 4

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