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CEP-33779 - CAS# 1257704-57-6 Size:Solid 10 mg 2-diamine hydrate ditetradecanoate

SKU: 22537900779

4.9
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CEP-33779 - CAS# 1257704-57-6 Size:Solid 10 mg 2-diamine hydrate ditetradecanoateCEP 33779 is a highly selective, orally active, small molecule inhibitor of JAK2. CEP 33779 induced regression of established colorectal tumors, reduced angiogenesis, and reduced proliferation of tumor cells. Tumor regression correlated with inhibition of STAT3 and NF B (RelA p65) activation in a CEP 33779 dose dependent manner. The ability of CEP 33779 to suppress growth of colorectal tumors by inhibiting the IL 6 JAK2 STAT3 signaling suggests a

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Description

2-diamine hydrate ditetradecanoate

S-phase arrest

1-2(3)4/h7-8

InChi: InChI=1S/2C10H14N2

T-5224 has been investigated in phase II human clinical trials

CEP-33779 - CAS# 1257704-57-6 Size:Solid 10 mg 2-diamine hydrate ditetradecanoateCEP 33779 is a highly selective, orally active, small molecule inhibitor of JAK2. CEP 33779 induced regression of established colorectal tumors, reduced angiogenesis, and reduced proliferation of tumor cells. Tumor regression correlated with inhibition of STAT3 and NF B (RelA p65) activation in a CEP 33779 dose dependent manner. The ability of CEP 33779 to suppress growth of colorectal tumors by inhibiting the IL 6 JAK2 STAT3 signaling suggests a

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