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PF-04449913 0077 AG 1749 sodium

SKU: 25819444867

4.1
USD105.00 USD146.00

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PF-04449913 0077 AG 1749 sodiumGlasdegib, also known as PF 04449913, is an orally bioavailable small molecule inhibitor of the Hedgehog (Hh) signaling pathway with potential antineoplastic activity. Hedgehog inhibitor PF 04449913 appears to inhibit Hh pathway signaling. The Hh signaling pathway plays an important role in cellular growth, differentiation and repair. Constitutive activation of Hh pathway signaling has been observed in various types of malignancies. Product

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Description

AG 1749 sodium

InChi: InChI=1S/C19H28N2O4

tumor cell proliferation and invasion

Solubility: DMSO: 100 mg/mL(136

J Neuroinflammation

PF-04449913 0077 AG 1749 sodiumGlasdegib, also known as PF 04449913, is an orally bioavailable small molecule inhibitor of the Hedgehog (Hh) signaling pathway with potential antineoplastic activity. Hedgehog inhibitor PF 04449913 appears to inhibit Hh pathway signaling. The Hh signaling pathway plays an important role in cellular growth, differentiation and repair. Constitutive activation of Hh pathway signaling has been observed in various types of malignancies. Product

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