ALK inhibitor 1 Catalog No.:M10174-2 AG-490 at 30 μM inhibits

AG-490 at 30 μM inhibits not only Epo-induced phosphorylation of wild-type JAK2 but also constitutive phosphorylation of the JAK2 V617F mutant

Smiles: O=C1NC(=O)S/C/1=C/C1=CC(=CC=C1)C(F)(F)F

2013 Sep 25

Formula: C27H34O14

CAS Number: 1047634-65-0

ALK inhibitor 1 Catalog No.:M10174-2 AG-490 at 30 μM inhibitsALK Inhibitor 1 is a novel and selective inhibitor for the ALK kinase. Product information CAS Number: 761436 81 1 Molecular Weight: 562. 48 Formula: C23H28BrN7O3S Chemical Name: 2 [(5 bromo 2 {[2 methoxy 4 (4 methylpiperazin 1 yl)phenyl]amino}pyrimidin 4 yl)amino] N methylbenzene 1 sulfonamide Smiles: CN1CCN(CC1)C1=CC(OC)=C(C=C1)NC1=NC(NC2=CC=CC=C2S(=O)(=O)NC)=C(Br)C=N1 InChiKey: FTSDLONCFCQDGA UHFFFAOYSA N InChi: InChI=1S C23H28BrN7O3S c1 25