Purvalanol A - CAS# 212844-53-6 60256 10)/b11-6+

10)/b11-6+

GSK 2983559

5-dimethyl-4-(4-hydroxy-3-isopropylbenzyl)phenoxy)methylphosphonicacid

15(3):234-45

It works by reducing lung fibrosis through downregulation of the production of growth factors and procollagens I and II

Purvalanol A - CAS# 212844-53-6 60256 10)/b11-6+Purvalanol A, CAS No. 212844 53 6, is a potent CDK inhibitor, which effectively suppresses Src mediated transformation by inhibiting both CDKs and c Src. indicating that the activation of CDKs contributes to the c Src transformation. Purvalanol A suppressed the c Src activity as effectively as the Src selective inhibitor PP2, and that it reverted the transformed morphology to a nearly normal shape with less cytotoxicity than PP2. Purvalanol A induced