(+)-Lafutidine 154 Obeticholic acid (INT-747) (10 mg/kg/day)

Obeticholic acid (INT-747) (10 mg/kg/day) completely reverted cholestasis induced by E217α

[Epub ahead of print] PubMed PMID: 31243340

Sodium ionophore III

Chemical Name: (4-((4-chloro-3-(trifluoromethyl)phenyl)sulfonyl)piperazin-1-yl)(4-(5-methyl-1H-pyrazol-1-yl)phenyl)methanone

2 or 1 days before virus challenge

(+)-Lafutidine 154 Obeticholic acid (INT-747) (10 mg/kg/day)(+) Lafutidine is an antagonist of histamine H2 receptor that inhibits gastric acid secretion Product information CAS Number: 118288 08 7 Molecular Weight: 431. 55 Formula: C22H29N3O4S Synonym: FRG 8813 Chemical Name: 2 (furan 2 ylmethylsulfinyl) N [(Z) 4 [4 (piperidin 1 ylmethyl)pyridin 2 yl]oxybut 2 enyl]acetamide Smiles: O=C(CS(=O)CC1=CC=CO1)NC C=C\COC1=CC(CN2CCCCC2)=CC=N1 InChiKey: KMZQAVXSMUKBPD DJWKRKHSSA N InChi: InChI=1S C22H29N3O4S c26 21(18