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Krauth-Siegel et al., studied the Y197S variant of GR and concluded the diminished accumulation of FAD-NADPH charge transfer and the overall decrease in the rate constants observed for reduction were evidence of Y197 directly participating in the flavin reduction event (Krauth-Siegel et al., 1998)

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observed that CP treatment caused a significant increase in MDA levels along with a reduction in CAT activity in liver tissue, suggesting that these changes disrupt the balance of the antioxidant system in the liver (1)

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170 These studies collectively illustrate that a wide range of phytochemicals, including terpenoids (oridonin, triptolide, atractylenolide I), flavonoids (SKN, galangin, engeletin), and phenolics (canolol), act through common and well-conserved inflammatory pathways

The biphasic nature of nitric oxide responses in tumor biolog