NIK SMI1 60295 ABT-100 (6

ABT-100 (6

Nawrocki ST

tolerability and clinical activity of VX-765

7-fold) in splenic weight when expressed as a percentage of total body weight (1

EW-7197 Hydrochloride suppresses the TGFβ-induced nuclear translocation of Smad2/3 in 4T1 cells and MCF10A cells

NIK SMI1 60295 ABT-100 (6NIK SMI1 is a highly potent and selective NF B inducing kinase (NIK) inhibitor with Ki of 0. 23 nM for NIK catalyzed hydrolysis of ATP to ADP. Product information CAS Number: 1660114 31 7 Molecular Weight: 365. 38 Formula: C20H19N3O4 Chemical Name: (R) 6 (3 ((3 Hydroxy 1 methyl 2 oxopyrrolidin 3 yl)ethynyl)phenyl) 4 methoxypicolinamide Smiles: COC1=CC(=NC(=C1)C1=CC(=CC=C1)C#C[C@]1(O)CCN(C)C1=O)C(N)=O InChiKey: LQSHXYHWYGKAMX FQEVSTJZSA N InChi: