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GSK429286A - CAS# 864082-47-3 Catalog No.:M6852-C Formula: C27H21N3O5

GSK429286A - CAS# 864082-47-3 Catalog No.:M6852-C Formula: C27H21N3O5

Name: GSK429286A - CAS# 864082-47-3 Catalog No.:M6852-C Formula: C27H21N3O5
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GSK429286A - CAS# 864082-47-3 Catalog No.:M6852-C Formula: C27H21N3O5GSK429286A, CAS No. 864082 47 3, is a selective Rho kinase inhibitor (IC50 values are 14, 780 and 1940 nM for ROCK1, RSK and p70S6K respectively). Reverses adrenalin induced contraction of the rat aortic ring (IC50 = 190 nM) and causes a dose dependent decrease in mean arterial blood pressure in spontaneous hypertensive rats. Orally active. Product information CAS Number: 864082 47 3 Molecular Weight: 432. 37 Formula: C21H16F4N4O2 Synonym: GSK 429286A

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Description

Formula: C27H21N3O5

Chemical Name: 2-[[4-(5-Benzothiazolylamino)-6-[(1

PubMed PMID: 27997653

PubMed PMID: 25296383

Clausen DM

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