NEIL2 Polyclonal Antibody, 100ul Peptide Modification Inherited mutations in BRCA1 and

Inherited mutations in BRCA1 and this gene

transformation and apoptosis

Disruption of this gene has been implicated in Carpenter syndrome as well as cancer

The mature peptide may be further cleaved into additional products (PMID: 20367554)

This enzyme is a multifunctional serine/threonine protein kinase with limited tissue distribution

NEIL2 Polyclonal Antibody, 100ul Peptide Modification Inherited mutations in BRCA1 andNEIL2 belongs to a class of DNA glycosylases homologous to the bacterial Fpg Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al., 2002